Description

Alatrofloxacin is a broad-spectrum fluoroquinolone antibiotic prodrug, designed for enhanced solubility and bioavailability in parenteral formulations. Its primary value lies in its potent activity against a wide range of Gram-positive and Gram-negative bacteria, including multi-drug resistant strains. This makes it a critical intermediate and active pharmaceutical ingredient (API) for research and development in the pharmaceutical industry, particularly for developing advanced injectable antibiotic therapies.

Application

• Pharmaceutical API Synthesis: Serves as a key intermediate in the production of injectable antibiotic formulations.
• Antimicrobial Research: Used in preclinical and clinical research to study the efficacy of advanced fluoroquinolone compounds.
• Veterinary Medicine Development: Investigated for potential applications in treating serious bacterial infections in animals.
• Hospital-Acquired Infection (HAI) Treatment R&D: Targeted for developing therapies against resistant pathogens common in clinical settings.
• Prodrug Mechanism Studies: Utilized in biochemical research to understand the activation and pharmacokinetics of prodrug antibiotic systems.

Basic Information

Product Name	Alatrofloxacin
CAS No.	146961-76-4
Molecular Formula	C20H20F3N4O7
Molecular Weight	485.39 g/mol
Synonyms	Alatrofloxacin; Trovafloxacin alaninyl hydrochloride; CP-116,517; (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, L-alaninamide hydrochloride; Trovafloxacin prodrug
EINECS	Contact for details

Quality Control

Our Alatrofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.