Description

2-Amino-5-Fluorobenzaldehyde is a versatile aromatic aldehyde building block characterized by its reactive amino and formyl functional groups. This compound matters for its critical role as a key intermediate in the synthesis of complex heterocyclic and pharmaceutical compounds. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing quinazoline, benzimidazole, or other fused heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Employed in the production of specialized fluorinated dyes and organic pigments for high-performance applications.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional organic materials.
• Academic and R&D Laboratories: Utilized in medicinal chemistry programs for hit-to-lead optimization and the exploration of new chemical entities.

Basic Information

Product Name	2-Amino-5-Fluorobenzaldehyde
CAS No.	146829-56-3
Molecular Formula	C7H6FNO
Molecular Weight	139.13 g/mol
Synonyms	5-Fluoro-2-aminobenzaldehyde; 2-Amino-5-fluorobenzenecarboxaldehyde; 5-Fluoroanthranilaldehyde; 5-Fluoro-2-formylaniline; 2-Formyl-4-fluoroaniline; 4-Fluoro-2-aminobenzaldehyde; Benzenecarboxaldehyde, 2-amino-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluorobenzaldehyde is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized (store under inert atmosphere), prolonged exposure to air and light should be avoided. For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.