Description

6-Pteridinepropanoic Acid, 2,4-Diamino-.Alpha.-(4-Carboxyphenyl)-.Alpha.-2-Propyn-1-Yl- is a complex, high-purity heterocyclic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical synthetic intermediate or a potential pharmacophore in the design of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery of new drugs, particularly in areas requiring sophisticated organic building blocks. The compound's unique structure, featuring pteridine, amino, carboxylic acid, and alkyne functional groups, makes it a versatile precursor for targeted synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying biological pathways due to its reactive alkyne group for click chemistry.
• Antifolate Analogue Synthesis: Potential precursor in the development of compounds targeting folate metabolism, relevant in oncology and antimicrobial research.
• High-Value Fine Chemical Production: Serves as a specialized intermediate in custom synthesis and contract manufacturing for the life sciences sector.

Basic Information

Product Name	6-Pteridinepropanoic Acid, 2,4-Diamino-.Alpha.-(4-Carboxyphenyl)-.Alpha.-2-Propyn-1-Yl-
CAS No.	146464-92-8
Molecular Formula	C21H17N5O4
Molecular Weight	403.39 g/mol
Synonyms	2,4-Diamino-α-(4-carboxyphenyl)-α-(2-propyn-1-yl)-6-pteridinepropanoic Acid; 2,4-Diamino-α-(4-carboxybenzyl)-α-propargyl-6-pteridinepropanoic Acid; α-(4-Carboxyphenyl)-α-(2-propynyl)-2,4-diamino-6-pteridinepropanoic Acid; 6-Pteridinepropanoic acid, 2,4-diamino-α-(4-carboxyphenyl)-α-2-propyn-1-yl-; (4-Carboxyphenyl)(prop-2-yn-1-yl)(2,4-diaminopteridin-6-yl)acetic acid; CAS 146464-92-8
EINECS	Contact for details

Quality Control

Our 6-Pteridinepropanoic Acid, 2,4-Diamino-.Alpha.-(4-Carboxyphenyl)-.Alpha.-2-Propyn-1-Yl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting all critical quality attributes. Our quality system is designed to support GMP-grade requirements for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.