Description

H-Tyr(So 3H)-Oh,Disodium Salt is a chemically modified, sulfated derivative of the amino acid tyrosine, presented as a stable disodium salt. This compound is a critical building block and intermediate in advanced biochemical research and pharmaceutical development, particularly for studying protein modifications and signaling pathways. It is essential for researchers and manufacturers in the fields of peptide synthesis, proteomics, and the development of novel therapeutic agents.

Application

• Peptide Synthesis Intermediate: A key protected and modified amino acid for the solid-phase and solution-phase synthesis of complex, sulfated peptides.
• Biochemical Research: Used as a standard or substrate in enzymatic studies related to tyrosine sulfation, a critical post-translational modification.
• Pharmaceutical Development: Serves as a crucial raw material in the R&D of peptide-based drugs targeting receptors that recognize sulfotyrosine motifs.
• Proteomics & Diagnostics: Employed in the development of assays and tools for detecting and quantifying sulfated proteins in biological samples.
• Enzyme Inhibition Studies: Useful for investigating the activity and inhibition of tyrosylprotein sulfotransferases (TPST).
• Academic Research: A valuable reagent for universities and research institutions studying cell signaling, inflammation, and coagulation pathways.

Basic Information

Product Name	H-Tyr(So 3H)-Oh,Disodium Salt
CAS No.	146386-55-2
Molecular Formula	C9H9NNa2O7S
Molecular Weight	321.21 g/mol
Synonyms	L-Tyrosine, O-sulfo-, disodium salt; Fmoc-Tyr(SO3H)-OH disodium salt (protected form); O-Sulfo-L-tyrosine disodium salt; Tyrosine O-sulfate disodium salt; H-Tyr(SO3Na)-OH; 2-Amino-3-(4-sulfonatooxyphenyl)propanoic acid disodium salt; Sulfotyrosine disodium salt
EINECS	Contact for details

Quality Control

Our H-Tyr(So 3H)-Oh,Disodium Salt is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to meet the demanding requirements of the pharmaceutical and biotechnology industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.