Description

Cftr (505-511) CAS NO 146289-28-3 is a synthetic peptide fragment corresponding to a specific sequence of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This high-purity biochemical is a critical research tool for studying protein function, structure, and interactions related to cystic fibrosis and ion channel biology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in targeted therapeutic development and molecular biology studies.

Application

• Biochemical Research: Used as a reference standard or antigen in studies of CFTR protein structure, function, and post-translational modifications.
• Antibody Production & Development: Serves as an immunogen for generating and characterizing sequence-specific polyclonal or monoclonal antibodies.
• Diagnostic Assay Development: Employed in the development and validation of ELISA, Western blot, or other immunoassays for detecting CFTR or related biomarkers.
• Drug Discovery & Screening: Acts as a target or competitor in high-throughput screening (HTS) assays to identify potential CFTR modulators or therapeutic compounds.
• Cell Signaling & Pathway Analysis: Utilized in studies investigating CFTR's role in cellular signaling pathways and its interactions with other proteins.
• Quality Control Reference: Functions as a purity standard in the quality control of other CFTR-related peptides or biological reagents.

Basic Information

Product Name	Cftr (505-511) CAS NO 146289-28-3
CAS No.	146289-28-3
Molecular Formula	C37H60N10O11S
Molecular Weight	852.99 g/mol
Synonyms	CFTR (505-511); CFTR Peptide Fragment 505-511; H-Cys-Phe-Thr-Arg-Lys-Cys-OH (Disulfide bridge: Cys505-Cys511); Cystic Fibrosis Transmembrane Conductance Regulator (505-511); Cyclo(505-511)CFTR; CFTR-derived peptide; CFTR modulator peptide; [Cys505, Cys511]CFTR(505-511)
EINECS	Contact for details

Quality Control

Our Cftr (505-511) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing purity, peptide content, and analytical results to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, lyophilized powder is recommended. Allow the vial to warm to room temperature before opening to minimize moisture absorption. Solutions should be prepared in appropriate buffers and used immediately or stored aliquoted at -80°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Composition	Within ±10% of theoretical values
Solubility	Soluble in water, dilute acetic acid, or suitable aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.