Description

2-Fluoro-3-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of halogenated aromatics.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where fluorine substitution enhances stability and performance.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other complex structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorinated and iodinated compound libraries.

Basic Information

Item	Details
Product Name	2-Fluoro-3-Iodobenzaldehyde
CAS No.	146137-83-9
Molecular Formula	C7H4FIO
Molecular Weight	250.01 g/mol
Synonyms	3-Iodo-2-fluorobenzaldehyde; 2-Fluoro-3-iodobenzenecarboxaldehyde; 3-Iodo-2-fluorobenzenecarboxaldehyde; o-Fluoro-m-iodobenzaldehyde; Benzaldehyde, 2-fluoro-3-iodo-; 146137-83-9; 2-Fluoro-3-iodo-benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Iodobenzaldehyde is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.