Description

2-Fluoro-5-(Trifluoromethyl)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block. This compound is highly valued for its unique electronic properties imparted by the fluorine and trifluoromethyl substituents, which are critical for modulating the reactivity and physicochemical characteristics of target molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific properties like chemical resistance, thermal stability, or unique optical characteristics.
• Organic Synthesis & Catalysis: Employed as a versatile electrophile in cross-coupling reactions, nucleophilic additions, and as a ligand precursor in organometallic catalysis.
• Chemical Research & Development: Utilized in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Benzaldehyde
CAS No.	146137-78-2
Molecular Formula	C8H4F4O
Molecular Weight	192.11 g/mol
Synonyms	2-Fluoro-5-(trifluoromethyl)benzaldehyde; 5-(Trifluoromethyl)-2-fluorobenzaldehyde; 2-Fluoro-alpha,alpha,α-trifluoro-p-tolualdehyde; 2-Fluoro-5-trifluoromethylbenzaldehyde; 2-Fluor-5-(trifluormethyl)benzaldehyd; Benzaldehyde, 2-fluoro-5-(trifluoromethyl)-; 146137-78-2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.