Description

2-Fluoro-5-Iodobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, including cross-coupling reactions like Suzuki and Sonogashira couplings.
• Liquid Crystal and OLED Materials: Employed in the creation of fluorinated and iodinated organic semiconductors and liquid crystal compounds for display and lighting technologies.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis due to its derivatizable aldehyde group.
• Fluorinated Dye and Pigment Synthesis: Acts as a building block for producing advanced fluorophores and colorants with improved lightfastness and spectral properties.

Basic Information

Product Name	2-Fluoro-5-Iodobenzaldehyde
CAS No.	146137-76-0
Molecular Formula	C7H4FIO
Molecular Weight	249.01 g/mol
Synonyms	5-Iodo-2-fluorobenzaldehyde; 2-Fluoro-5-iodobenzenecarboxaldehyde; 5-Iodo-2-fluorobenzenecarboxaldehyde; Benzaldehyde, 2-fluoro-5-iodo-; 146137-76-0; 2-Fluoro-5-iodo-benzaldehyde; 2-Fluoro-5-iodobenzaldehyde (contains stabilizer); 2-Fluoro-5-iodo-1-benzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodobenzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.