Description

Proteoglycan-Lb is a high-purity, biologically active glycosaminoglycan-protein complex, identified by CAS No. 145892-90-6. This compound is essential for research and development in advanced biomaterials and regenerative medicine due to its critical role in cellular signaling and extracellular matrix structure. It is primarily needed by biotechnology, pharmaceutical, and advanced cosmetic industries for applications in tissue engineering, drug delivery systems, and high-performance skincare formulations.

Application

• Biomedical Research: Used as a key component in studies of cartilage repair, osteoarthritis mechanisms, and extracellular matrix biology.
• Tissue Engineering Scaffolds: Incorporated into hydrogels and 3D matrices to promote cell adhesion, proliferation, and differentiation for regenerative therapies.
• Advanced Drug Delivery: Serves as a functional carrier or targeting moiety in novel delivery systems for proteins, growth factors, and nucleic acids.
• Cosmeceuticals: Formulated into high-end anti-aging and skin-repair products for its hydrating and skin-barrier reinforcing properties.
• Diagnostic Reagent Development: Employed in the production of assays and kits for detecting biomarkers related to connective tissue disorders.
• Cell Culture Media Supplement: Enhances the growth and maintenance of specialized cell lines, such as chondrocytes and stem cells, in vitro.

Basic Information

Item	Details
Product Name	Proteoglycan-Lb
CAS No.	145892-90-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Proteoglycan LB; Proteoglycan Lb Fraction; 145892-90-6; Proteoglycan (bovine); Cartilage Proteoglycan; Aggrecan; Chondroitin Sulfate Proteoglycan; Extracellular Matrix Proteoglycan
EINECS	Contact for details

Quality Control

Our Proteoglycan-Lb is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, SDS-PAGE for molecular weight distribution, and biological activity assays to ensure consistency and performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or desiccant after each use to maintain integrity. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Protein Content	15 - 30%
Glycosaminoglycan Content	70 - 85%
Biological Activity	Confirmed by cell-based assay
Endotoxin Level	< 1.0 EU/mg
Moisture Content (KF)	< 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.