Description

Ragweed Antigen K is a highly purified, standardized allergen extract derived from ragweed pollen, specifically formulated for diagnostic and research applications. This product is essential for the development and quality control of allergy diagnostics, including skin prick tests and in-vitro immunoassays. It serves as a critical raw material for pharmaceutical companies, diagnostic kit manufacturers, and research institutions focused on immunology and allergic disease.

Application

• Allergy Diagnostic Kits: Primary component in the manufacture of in-vitro immunoassays (e.g., ELISA, ImmunoCAP) for the specific detection of ragweed pollen IgE antibodies in patient serum.
• Skin Prick Test (SPT) Solutions: Used as the active allergenic ingredient in solutions for epicutaneous testing to diagnose type I hypersensitivity to ragweed.
• Allergen Standardization & Reference: Serves as a reference standard for the potency calibration and batch-to-batch consistency testing of other allergen extracts.
• Immunotherapy Research: Key reagent in preclinical and clinical research for developing and evaluating specific allergen immunotherapy (SIT) treatments.
• Immunological Studies: Used in research to study IgE-mediated immune responses, mast cell/basophil activation, and the molecular mechanisms of allergic sensitization.
• Quality Control (QC) Testing: Employed by manufacturers as a control antigen to validate the performance and specificity of diagnostic platforms.

Basic Information

Product Name	Ragweed Antigen K
CAS No.	145892-07-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ragweed Allergen Extract; Short Ragweed Pollen Allergen Extract; Ambrosia artemisiifolia Allergen Extract; Amb a K; Antigen K (Ragweed); Allergen K (Ragweed); Ragweed Pollen Antigen K; Diagnostic Ragweed Antigen
EINECS	Contact for details

Quality Control

Our Ragweed Antigen K is manufactured under strict quality management systems. Each batch is characterized for protein content, allergenic activity, and specificity using immunochemical methods such as crossed immunoelectrophoresis (CIE) and IgE immunoblotting. A comprehensive Certificate of Analysis (COA) detailing purity, potency (in-house units or major allergen content), and absence of specified contaminants is provided to ensure reliability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot as necessary to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (Immunodiffusion)	Conforms to reference
Protein Content (Bradford/Lowry)	≥ 1.0 mg/mL
pH	7.0 - 8.5
Sterility (Membrane Filtration)	Sterile
Endotoxin (LAL)	< 10 EU/mL
Potency (In-house RAST/ELISA Inhibition)	10,000 - 50,000 AU/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.