Description

(R)-Methocarbamol CAS NO 145841-69-6 is the single enantiomer form of the centrally acting muscle relaxant methocarbamol. This specific stereoisomer is of significant interest in pharmaceutical research and development for its potential role in creating more targeted and efficacious therapeutic agents with potentially reduced side-effect profiles. It is primarily utilized by pharmaceutical companies, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in advanced chiral drug synthesis and pharmacological studies.

Application

• Chiral Pharmaceutical Intermediate: Serves as a key building block in the research and synthesis of novel enantiomerically pure muscle relaxants and related central nervous system (CNS) active compounds.
• Pharmacological Reference Standard: Used as a high-purity standard in analytical method development, validation, and quality control testing for methocarbamol and its enantiomers.
• Mechanism of Action Studies: Employed in preclinical research to investigate the stereospecificity of methocarbamol's activity, helping to elucidate its precise biological targets and metabolic pathways.
• Active Pharmaceutical Ingredient (API) Development: A critical starting material for developing new drug candidates where the (R)-enantiomer is the therapeutically desired or more active form.
• Process Chemistry & Scale-Up: Used in optimizing asymmetric synthesis routes and scaling up production processes for chiral drugs.

Basic Information

Product Name	(R)-Methocarbamol
CAS No.	145841-69-6
Molecular Formula	C11H15NO5
Molecular Weight	241.24 g/mol
Synonyms	(R)-3-(2-Methoxyphenoxy)-1,2-propanediol 1-carbamate; (R)-Guaiacol glycerol ether carbamate; (R)-Methocarbamol; Dextro-Methocarbamol; (R)-Robaxin; (2R)-3-(2-Methoxyphenoxy)propane-1,2-diyl dicarbamate; (R)-2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate
EINECS	Contact for details

Quality Control

Our (R)-Methocarbamol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets stringent specifications for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic and should be kept under inert conditions for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (R)-enantiomer
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.