Description

6-Amino-2,3-Difluorobenzeneethanol is a versatile fluorinated aromatic amine building block with significant synthetic utility. Its molecular structure, featuring both an amino group and a fluorinated benzene ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical and advanced materials sectors for the development of new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorine and amine functionalities into polymer backbones, enhancing material properties like chemical resistance and surface energy.
• Dye & Pigment Manufacturing: Acts as an intermediate for creating specialized fluorinated dyes with unique color fastness and spectral properties.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex aromatic amines.

Basic Information

Product Name	6-Amino-2,3-Difluorobenzeneethanol
CAS No.	145689-33-4
Molecular Formula	C8H9F2NO
Molecular Weight	173.16 g/mol
Synonyms	2-(6-Amino-2,3-difluorophenyl)ethanol; 2,3-Difluoro-6-(2-hydroxyethyl)aniline; 6-Amino-2,3-difluorophenethyl alcohol; 2-(6-Amino-2,3-difluorophenyl)ethan-1-ol; 145689-33-4; 2,3-Difluoro-6-(2-hydroxyethyl)benzenamine; Benzenethanol, 6-amino-2,3-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 6-Amino-2,3-Difluorobenzeneethanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.