Description

(D-Tyr1,n-Me-Phe3)-Neuropeptide Ff CAS NO 145274-93-7 is a synthetic, biologically active peptide analog designed for advanced research and development. This compound is significant for its role in studying neuropeptide FF (NPFF) receptor systems, which are involved in modulating pain perception, opioid tolerance, and various physiological functions. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, analgesic drug discovery, and neuroendocrine research.

Application

• Neuroscience Research: A critical tool for investigating the NPFF receptor system's role in pain modulation, opioid-induced hyperalgesia, and tolerance.
• Drug Discovery & Development: Serves as a reference standard or lead compound in the development of novel analgesic and neuropharmacological agents.
• Biochemical Assays: Used in receptor binding studies, functional cellular assays (e.g., calcium flux, cAMP), and signal transduction pathway analysis.
• Pharmacological Studies: Employed in in vitro and in vivo models to study the physiological effects of NPFF system modulation.
• Academic & Clinical Research: Supports fundamental research into neuropeptide functions related to cardiovascular regulation, food intake, and stress responses.
• Peptide Chemistry Reference: Acts as a specific example for studying structure-activity relationships (SAR) in peptide design and modification.

Basic Information

Product Name	(D-Tyr1,n-Me-Phe3)-Neuropeptide Ff
CAS No.	145274-93-7
Molecular Formula	C52H68N12O11
Molecular Weight	1013.2 g/mol
Synonyms	[D-Tyr1, N-Me-Phe3] Neuropeptide FF; (D-Tyr1,N-Me-Phe3)NPFF; D-Tyr-Leu-(N-Me)Phe-Gln-Pro-Gln-Arg-Phe-NH2; 1-Deamino-2-[D-tyrosyl]-6-[N-methylphenylalanyl] neuropeptide FF; Neuropeptide FF analog (D-Tyr1, N-Me-Phe3); NPFF analog; F8Famide analog; Anti-opioid neuropeptide analog
EINECS	Contact for details

Quality Control

Our (D-Tyr1,n-Me-Phe3)-Neuropeptide Ff is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the rigorous demands of pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.