Description

5-Hydroxy-L-Tryptophan Hydrate is a naturally occurring amino acid derivative and a direct metabolic precursor to the neurotransmitter serotonin. This compound matters for its critical role in supporting neurological and metabolic functions, making it a valuable intermediate for high-value applications. It is primarily needed by manufacturers in the pharmaceutical, nutraceutical, and advanced biochemical research sectors for the development of therapeutic agents and dietary supplements.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of serotonin-related drugs and neurological medications.
• Dietary Supplements: Used as an active ingredient in nutraceutical formulations aimed at supporting mood, sleep, and cognitive health.
• Biochemical Research: Essential reference standard and reagent in neuroscience, pharmacology, and metabolic pathway studies.
• Precursor for Fine Chemicals: Serves as a starting material for the synthesis of more complex indole alkaloids and specialized organic compounds.
• Cosmeceutical Applications: Investigated for use in topical formulations targeting skin health and wellness due to its antioxidant properties.

Basic Information

Product Name	5-Hydroxy-L-Tryptophan Hydrate
CAS No.	145224-90-4
Molecular Formula	C11H12N2O3 • xH2O
Molecular Weight	220.23 (Anhydrous basis)
Synonyms	5-HTP Hydrate; L-5-Hydroxytryptophan Hydrate; Oxitriptan Hydrate; 5-Hydroxy-L-Tryptophan Monohydrate; (S)-5-Hydroxytryptophan Hydrate; 5-HTP; L-5-HTP; 3-(5-Hydroxy-1H-indol-3-yl)-L-alanine Hydrate
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-L-Tryptophan Hydrate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and nutraceutical use. Certificates of Analysis (COA) are available upon request, detailing compliance with relevant in-house and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	≤12.0%
Specific Rotation	-30.0° to -34.0° (c=1 in H2O)
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.