Description

(4-Aminobutanoyl)Melittin is a chemically modified derivative of the principal bioactive peptide, melittin, found in bee venom. This modification, which introduces a 4-aminobutanoyl group, is designed to alter the peptide's properties for enhanced research and development applications, particularly in studying membrane interactions and cytotoxicity. It serves as a critical tool for researchers and developers in the fields of pharmaceutical discovery, biophysical research, and antimicrobial agent development.

Application

• Biophysical Research: Used as a model peptide to study the mechanisms of pore formation, membrane lysis, and lipid bilayer interactions.
• Drug Discovery & Development: Acts as a lead compound or a tool for investigating novel anticancer, antimicrobial, and anti-inflammatory agents.
• Cell Biology Studies: Employed in assays to understand cell membrane permeability, apoptosis induction, and signal transduction pathways.
• Toxin & Venom Research: Serves as a reference standard or a modified toxin analog for comparative studies on natural bee venom components.
• Peptide Engineering: Provides a backbone for further chemical modifications to create peptides with tailored stability, activity, or targeting properties.
• Academic & Industrial R&D: Essential for universities, research institutes, and biotech companies focused on peptide therapeutics and molecular biology.

Basic Information

Item	Detail
Product Name	(4-Aminobutanoyl)Melittin
CAS No.	145204-12-2
Molecular Formula	C₁₃₁H₂₂₉N₃₉O₃₁
Molecular Weight	2846.5 g/mol (approx.)
Synonyms	4-Aminobutanoyl-Melittin; GABA-Melittin; γ-Aminobutyryl-Melittin; Melittin amide derivative; Nε-(4-Aminobutanoyl)Melittin; Modified melittin peptide; Synthetic melittin analog; Apitoxin derivative
EINECS	Contact for details

Quality Control

Our (4-Aminobutanoyl)Melittin is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous internal quality standards to meet the demands of pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.