Description

Scrub Typhus Antigen 22 is a highly purified, specific antigen derived from *Orientia tsutsugamushi*, the causative agent of scrub typhus. This product is critical for the development and quality control of sensitive and accurate diagnostic assays, including ELISA, immunoblotting, and lateral flow tests. It is an essential reagent for in-vitro diagnostic (IVD) manufacturers, clinical research laboratories, and public health institutions engaged in the surveillance, diagnosis, and study of this vector-borne disease.

Application

• Primary Component in Diagnostic Kits: Core antigen for the development and production of ELISA, immunofluorescence assay (IFA), and rapid diagnostic test (RDT) kits for scrub typhus.
• Clinical Research & Assay Development: Used as a reference standard in research laboratories to validate new diagnostic methods and study host immune responses.
• Serological Testing & Surveillance: Employed in public health laboratories for seroprevalence studies and epidemiological surveillance of scrub typhus in endemic regions.
• Quality Control & Calibration: Serves as a positive control and calibrator for ensuring the consistency and accuracy of commercial and in-house diagnostic assays.
• Antibody Detection & Characterization: Utilized to detect and characterize specific IgM and IgG antibodies in patient serum samples.
• Vaccine Research: Potential use as an immunogen or target antigen in the research and development of scrub typhus vaccines.

Basic Information

Item	Detail
Product Name	Scrub Typhus Antigen 22
CAS No.	145138-48-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Orientia tsutsugamushi Antigen 22; Scrub Typhus Rickettsia Antigen; Tsutsugamushi Disease Antigen; Rickettsia tsutsugamushi Antigen; OT-22 Antigen; Scrub Typhus Diagnostic Antigen; ST Ag 22
EINECS	Contact for details

Quality Control

Our Scrub Typhus Antigen 22 is manufactured under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure high specificity, purity, and lot-to-lot consistency, suitable for in-vitro diagnostic use. Quality is verified through methods including SDS-PAGE, Western Blot, and functional ELISA testing against standard reference sera. A comprehensive Certificate of Analysis (COA) detailing purity, protein concentration, and reactivity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C or below. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (Western Blot)	Reacts specifically with anti-Orientia tsutsugamushi antibodies
Purity (SDS-PAGE)	> 90% (Major band at ~22 kDa)
Protein Concentration	As per COA (Typically 0.5 - 2.0 mg/mL)
Functional Activity (ELISA)	Positive reactivity with confirmed positive human serum
Endotoxin Level	< 1.0 EU/µg (LAL test)
Sterility (Bacteriology)	No growth observed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.