Description

Fmoc-Glu-Ome CAS NO 145038-49-9 is a protected amino acid derivative, specifically the Fmoc (9-fluorenylmethoxycarbonyl) ester of glutamic acid methyl ester. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers involved in developing therapeutic peptides, biochemical probes, and novel materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key monomer for the automated, stepwise construction of custom peptide sequences.
• Pharmaceutical Research & Development: For synthesizing peptide-based drug candidates, hormone analogs, and diagnostic agents.
• Bioconjugation & Probe Development: Used to introduce glutamic acid residues with orthogonal protecting groups for site-specific labeling or cross-linking.
• Combinatorial Chemistry Libraries: Serves as a variable building block in the generation of diverse peptide libraries for high-throughput screening.
• Academic & Institutional Research: Fundamental studies in biochemistry, enzymology, and structural biology requiring custom peptides.
• Fine Chemical Intermediate: For the custom synthesis of more complex, glutamic acid-containing organic molecules.

Basic Information

Product Name	Fmoc-Glu-Ome
CAS No.	145038-49-9
Molecular Formula	C22H23NO6
Molecular Weight	397.42 g/mol
Synonyms	Fmoc-L-glutamic acid 5-methyl ester; Fmoc-Glu(OMe)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 1-methyl ester; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid 1-methyl ester; Fmoc-Glu(OMe); Fmoc-L-Glu-OMe; N-Fmoc-L-glutamic acid α-methyl ester; N-α-Fmoc-L-glutamic acid 1-methyl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Glu-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric integrity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Specific Rotation	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.