Description

Tauro--Muricholic Acid (Sodium Salt) is a conjugated bile acid derivative, specifically the taurine conjugate of muricholic acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key metabolite and signaling molecule in lipid metabolism and bile acid homeostasis. It is primarily utilized by researchers and manufacturers in the life sciences sector for advanced studies in hepatology, gastroenterology, and metabolic disease. The product is supplied as a high-purity reference standard and biochemical reagent.

Application

• Biochemical Research: Used as a critical reference standard and reagent for studying bile acid metabolism, transport, and signaling pathways.
• Pharmaceutical Development: Serves as a key intermediate or active metabolite in the research and development of therapeutics for liver diseases, cholestasis, and metabolic disorders.
• Cell Culture & In Vitro Studies: Employed in cell-based assays to investigate the effects of bile acids on cell viability, inflammation, and gene expression.
• Analytical Standard: Essential for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) used in bioanalysis and pharmacokinetic studies.
• Metabolomics & Biomarker Discovery: A vital compound in profiling bile acid signatures in biological samples for disease biomarker identification.
• Enzymology Studies: Used as a substrate or product in enzymatic assays related to bile acid synthesis and conjugation.

Basic Information

Product Name	Tauro--Muricholic Acid (Sodium Salt)
CAS No.	145022-92-0
Molecular Formula	C26H44NNaO7S
Molecular Weight	537.69 g/mol
Synonyms	Sodium Tauromuricholate; Tauromuricholic Acid Sodium Salt; Tauro-β-muricholic Acid Sodium Salt; T-β-MCA (Na); 3α,6β,7β-Trihydroxy-5β-cholan-24-oyltaurine Sodium Salt; N-[(3α,5β,6β,7β)-3,6,7-Trihydroxy-24-oxocholan-24-yl]taurine Sodium Salt; Tauro-β-muricholate Sodium; TMCA (Na)
EINECS	Contact for details

Quality Control

Our Tauro--Muricholic Acid (Sodium Salt) is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC for purity, NMR and MS for structural confirmation, and other relevant tests. Our quality commitment supports research requiring high-purity reference standards and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.