Description

4-Chloro-5-(Methylsulfanyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters because it serves as a critical precursor for the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Tool Compound: Serves as a starting material for synthesizing probes to study enzyme function and cellular signaling pathways.
• Agrochemical Research: Potential intermediate in the synthesis of novel herbicides or fungicides, leveraging its heterocyclic core.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule development.
• Academic Research: Used in university laboratories for methodological studies in heterocyclic chemistry and new reaction development.

Basic Information

Product Name	4-Chloro-5-(Methylsulfanyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	144927-56-0
Molecular Formula	C7H6ClN3S
Molecular Weight	199.66 g/mol
Synonyms	4-Chloro-5-(methylthio)-7H-pyrrolo[2,3-d]pyrimidine; 5-(Methylsulfanyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-methylsulfanyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-(methylthio)-; 4-Chloro-5-methylthio-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-(methylmercapto)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-(Methylsulfanyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.