Description

1-Acetoxy-4-(n-Acetyl-L-Cysteinyl)-2-Butanone is a specialized biochemical intermediate featuring a unique structure that combines a butanone backbone with acetylated cysteine and acetoxy functional groups. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel drug candidates and bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways.
• Peptide & Protein Research: Used in the study and modification of cysteine-containing peptides and proteins, leveraging its acetyl-L-cysteinyl moiety.
• Bioconjugation Chemistry: Acts as a versatile linker or functional handle for attaching payloads to biomolecules in antibody-drug conjugate (ADC) research.
• Chemical Biology Probes: Employed in the development of activity-based probes (ABPs) to study enzyme function and mechanism.
• Fine Chemical Synthesis: Utilized as a building block for creating complex, high-value specialty chemicals with specific chiral and functional properties.
• Academic & Institutional Research: Supports fundamental research in organic synthesis, medicinal chemistry, and biochemical studies.

Basic Information

Product Name	1-Acetoxy-4-(n-Acetyl-L-Cysteinyl)-2-Butanone
CAS No.	144889-52-1
Molecular Formula	C11H17NO6S
Molecular Weight	291.32 g/mol
Synonyms	4-(N-Acetyl-L-cysteinyl)-1-acetoxy-2-butanone; 1-Acetoxy-4-(N-acetyl-L-cysteinyl)-2-butanone; 2-Butanone, 1-(acetyloxy)-4-[(2R)-2-(acetylamino)-3-mercapto-1-oxopropyl]-; (2R)-2-Acetamido-3-mercapto-1-[4-(acetyloxy)-2-oxobutyl]propanoic Acid; N-Acetyl-S-[3-(acetyloxy)-2-oxopropyl]-L-cysteine; AAB; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 1-Acetoxy-4-(n-Acetyl-L-Cysteinyl)-2-Butanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain stability. Keep container tightly sealed in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Purity (HPLC, Area %)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.