Description

Glycine, n-[4-[1-[[(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]carbonyl]propyl]phenyl]-, 1,1-dimethylethyl ester is a high-purity, specialized chemical intermediate with a complex molecular architecture. This compound matters for its role as a critical building block in advanced pharmaceutical synthesis, particularly for the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of innovative drugs, where precise chemical structure and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially in research for new drug candidates.
• Biochemical Research: Used in laboratory settings for studying enzyme interactions, receptor binding, and other molecular biology applications.
• Protease Inhibitor Development: Its structural features make it relevant for research into inhibitors targeting specific enzymatic pathways.
• Custom Synthesis: Employed by fine chemical manufacturers for producing bespoke compounds under contract research and development (CRD) agreements.

Basic Information

Product Name	Glycine, n-[4-[1-[[(6-Amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]carbonyl]propyl]phenyl]-, 1,1-dimethylethyl ester
CAS No.	144872-01-5
Molecular Formula	C₂₈H₄₃N₅O₅
Molecular Weight	529.68 g/mol
Synonyms	tert-Butyl N-[4-[1-[[(6-amino-1,3-dipropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)carbamoyl]propyl]phenyl]glycinate; BIBR 953 ZW; BIBR-953; BIBR 953; UNII-8JQ5607IO5; 8JQ5607IO5; Glycine, N-[4-[1-[[(6-amino-2,4-dioxo-1,3-dipropyl-1,2,3,4-tetrahydro-5-pyrimidinyl)amino]carbonyl]propyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. While typically supplied as a high-purity research chemical, specifications can be aligned with cGMP (current Good Manufacturing Practice) standards for pharmaceutical development. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.