Description

2-Amino-3-Fluorobenzotrifluoride is a high-value fluorinated aromatic amine building block, essential for introducing both fluorine and amino functionalities into complex molecular architectures. Its primary commercial significance lies in its role as a versatile intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl and fluorine groups enhance metabolic stability and bioavailability. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorinated moiety improves efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent for developing specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a scaffold for constructing complex heterocycles in medicinal chemistry.
• Dye and Pigment Intermediate: Utilized in the manufacture of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	2-Amino-3-Fluorobenzotrifluoride
CAS No.	144851-61-6
Molecular Formula	C7H5F4N
Molecular Weight	179.12 g/mol
Synonyms	3-Fluoro-2-aminobenzotrifluoride; 2-Amino-α,α,α,3-tetrafluorotoluene; 3-Fluoro-2-aminotrifluorotoluene; 2-Amino-3-fluorobenzylidene trifluoride; 3-Fluoro-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-3-fluoroaniline; Benzenamine, 3-fluoro-2-(trifluoromethyl)-; 144851-61-6
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.