Description

Diapause Hormone (Silkworm, 1-24) is a synthetic peptide hormone analog that replicates the biological activity of the natural diapause hormone found in the silkworm, Bombyx mori. This compound is crucial for research and development in the fields of insect physiology and pest management, as it directly influences the critical life cycle process of diapause. It is an essential biochemical tool for entomologists, molecular biologists, and agrochemical researchers focused on studying insect development, reproduction, and creating novel, targeted insect growth regulators. The CAS number for this specific peptide is 144774-18-5.

Application

• Insect Physiology Research: Fundamental studies on the molecular mechanisms controlling diapause induction and termination in Lepidoptera and other insect orders.
• Agrochemical R&D: Screening and development of next-generation, species-specific insect growth regulators (IGRs) that mimic or disrupt diapause hormone signaling for pest control.
• Molecular Biology: Investigation of peptide hormone-receptor interactions, signal transduction pathways, and gene expression profiles related to insect dormancy and development.
• Comparative Endocrinology: Studies on the evolution and functional diversity of peptide hormones across different insect species.
• Biotechnology: Potential use in sericulture (silkworm farming) for manipulating breeding cycles and silk production efficiency.

Basic Information

Product Name	Diapause Hormone (Silkworm, 1-24)
CAS No.	144774-18-5
Molecular Formula	C₁₁₉H₁₈₈N₃₈O₃₈
Molecular Weight	2635.9 g/mol
Synonyms	Bombyx Diapause Hormone (1-24); DH (1-24); Diapause Hormone Fragment 1-24; Silkworm Diapause Hormone Peptide; [Ser¹, Ile², Asn³, Ser⁴, Glu⁵, Asp⁶, Leu⁷, Glu⁸, Lys⁹, Glu¹⁰, Ala¹¹, Val¹², Gly¹³, Ala¹⁴, Val¹⁵, Arg¹⁶, Leu¹⁷, Phe¹⁸, Thr¹⁹, Pro²⁰, Arg²¹, Leu²², Arg²³, Phe²⁴]-Diapause Hormone (1-24); Bom-DH (1-24).
EINECS	Contact for details

Quality Control

Our Diapause Hormone (Silkworm, 1-24) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and peptide content specifications are met. Standard quality control includes reversed-phase HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.