Description

3,7-Diamino-2-Hydroxyheptanoyl-Leucyl-Proline is a synthetic peptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying enzyme inhibition, particularly in relation to metalloproteases and other proteolytic systems. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of potential drug candidates targeting specific enzymatic pathways.
• Biochemical Assay Development: Used as a substrate or inhibitor in enzymatic assays to study the kinetics and mechanisms of proteases and related enzymes.
• Proteomics and Molecular Biology: Employed in research focused on protein-protein interactions, signal transduction, and cellular regulation mechanisms.
• Academic Research: Serves as a valuable tool in university and institutional labs for fundamental studies in medicinal chemistry and biochemistry.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development, validation, and quality control in GLP/GMP environments.

Basic Information

Product Name	3,7-Diamino-2-Hydroxyheptanoyl-Leucyl-Proline
CAS No.	144732-34-3
Molecular Formula	C19H35N5O5
Molecular Weight	413.51 g/mol
Synonyms	3,7-Diamino-2-hydroxyheptanoyl-L-leucyl-L-proline; DAH-Leu-Pro; (2S)-2-[[(2S)-2-Amino-6-[[(2S)-1-[(2S)-2-aminopentanoyl]pyrrolidin-2-yl]formamido]hexanoyl]amino]-5-guanidinopentanoic acid (related structure); Leucylproline derivative inhibitor; Peptidomimetic research compound; CAS 144732-34-3
EINECS	Contact for details

Quality Control

Our 3,7-Diamino-2-Hydroxyheptanoyl-Leucyl-Proline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research chemicals, and specifications can be tailored to meet specific project requirements, including those for GMP starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.