Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(3,5-Dimethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-8-(Trifluoromethyl)- is a high-value, structurally complex fluoroquinolone derivative. This compound is critical for pharmaceutical research and development, serving as a key advanced intermediate in the synthesis of novel antibacterial agents. It is primarily required by pharmaceutical manufacturers and R&D organizations focused on developing next-generation antibiotics to combat resistant bacterial strains.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel fluoroquinolone antibiotics.
• Antibacterial Drug Discovery: Used in medicinal chemistry research to develop new compounds targeting DNA gyrase and topoisomerase IV enzymes.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final stages of manufacturing specific, potent antibacterial APIs.
• Biochemical Research: Serves as a reference standard or probe in studies of bacterial resistance mechanisms and drug-target interactions.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for complex pharmaceutical molecules.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(3,5-Dimethyl-1-Piperazinyl)-6-Fluoro-1,4-Dihydro-4-Oxo-8-(Trifluoromethyl)-
CAS No.	144634-02-6
Molecular Formula	C20H22F4N4O3
Molecular Weight	442.41 g/mol
Synonyms	1-Cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-8-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(3,5-dimethyl-1-piperazinyl)-8-(trifluoromethyl)-3-quinolinecarboxylic Acid; 8-Trifluoromethyl-1-cyclopropyl-7-(3,5-dimethylpiperazin-1-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Gatifloxacin Intermediate; AM-1155 Intermediate; LB20304a Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.