Description

3-Bromo-5-Fluoro-2-Iodoaniline is a high-purity, multi-halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for imaging and diagnostic applications due to the iodine atom's potential for radiolabeling.
• Cross-Coupling Reactions: An essential substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl and conjugated systems.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Iodoaniline
CAS No.	144580-08-5
Molecular Formula	C6H4BrFIN
Molecular Weight	315.91 g/mol
Synonyms	2-Iodo-3-bromo-5-fluoroaniline; 3-Bromo-5-fluoro-2-iodobenzenamine; Benzenamine, 3-bromo-5-fluoro-2-iodo-; 1-Amino-3-bromo-5-fluoro-2-iodobenzene; 2-Amino-4-bromo-6-fluoro-1-iodobenzene; 144580-08-5; 3-Br-5-F-2-I-aniline
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-2-Iodoaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.