Description

1-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-D-Proline CAS NO 144575-00-8 is a specialized, high-purity dipeptide derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications in peptide synthesis and medicinal chemistry research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected proline derivative, enabling the construction of specific peptide sequences.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of protease inhibitors or other receptor-targeting molecules.
• Bioconjugation: Employed in the preparation of peptide conjugates for diagnostic or therapeutic purposes.
• Fine Chemical Synthesis: Acts as a chiral synthon in the asymmetric synthesis of non-peptidic compounds requiring proline-like stereocenters.

Basic Information

Product Name	1-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-D-Proline
CAS No.	144575-00-8
Molecular Formula	C25H24N2O5
Molecular Weight	432.47 g/mol
Synonyms	Fmoc-L-Pro-D-Pro-OH; Fmoc-Pro-Pro-OH (L-D); 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-D-proline; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolyl-D-proline; Fmoc-Pro-Pro; Fmoc-L-Pro-D-Pro; (S)-1-((((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carbonyl)-D-proline
EINECS	Contact for details

Quality Control

Our 1-[1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolyl]-D-Proline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.