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2-(4-{[(Benzyloxy)Carbonyl]Amino}-2-Oxo-1,2-Dihydropyrimidin-1-Yl)Acetic Acid CAS NO 144564-95-4


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CAS No.:144564-95-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(4-{[(Benzyloxy)Carbonyl]Amino}-2-Oxo-1,2-Dihydropyrimidin-1-Yl)Acetic Acid is a high-purity, non-natural pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized structure, which allows for precise modifications in the development of novel chemical entities. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of nucleoside analogs and other biologically active molecules.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside and nucleotide analogs with potential therapeutic applications.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting viral or oncological diseases.
  • Bioconjugation Chemistry: The carboxylic acid functional group enables coupling reactions for labeling or modifying biomolecules.
  • Chemical Biology Probes: Serves as a precursor for creating specialized probes to study enzymatic mechanisms or cellular processes.
  • Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom production of complex, high-value compounds.
  • Academic Research: Utilized in universities and research institutes for fundamental studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name 2-(4-{[(Benzyloxy)Carbonyl]Amino}-2-Oxo-1,2-Dihydropyrimidin-1-Yl)Acetic Acid
CAS No. 144564-95-4
Molecular Formula C14H13N3O5
Molecular Weight 303.27 g/mol
Synonyms 1-Carboxymethyl-4-(N-benzyloxycarbonyl)amino-2-pyrimidinone; 2-[[4-[(Benzyloxy)carbonyl]amino-2-oxo-1(2H)-pyrimidinyl]]acetic Acid; 2-({4-[(Benzyloxycarbonyl)amino]-2-oxo-1,2-dihydropyrimidin-1-yl})acetic Acid; N-Cbz-4-aminouracil-1-acetic Acid; 1-(Carboxymethyl)-4-[(phenylmethoxy)carbonyl]amino-2(1H)-pyrimidinone; 144564-95-4; 2-(4-(N-Cbz-amino)-2-oxo-1,2-dihydropyrimidin-1-yl)acetic Acid
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Quality Control

Our 2-(4-{[(Benzyloxy)Carbonyl]Amino}-2-Oxo-1,2-Dihydropyrimidin-1-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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