Description

H-Tyr-Pro-Trp-Gly-Nh2 is a synthetic tetrapeptide amide with the CAS number 144450-13-5. This compound is a crucial building block in advanced pharmaceutical research and development, particularly in the design of novel peptide-based therapeutics and diagnostic agents. It is primarily sought by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, metabolic studies, and biochemical assay development.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the production of more complex peptide drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Drug Discovery: Employed in high-throughput screening (HTS) libraries and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Peptide Synthesis: Acts as a fundamental fragment in solid-phase and solution-phase peptide synthesis (SPPS) for constructing longer peptide chains.
• Diagnostic Development: Utilized in the development of peptide-based biomarkers, immunoassays, and diagnostic kits.

Basic Information

Product Name	H-Tyr-Pro-Trp-Gly-Nh2
CAS No.	144450-13-5
Molecular Formula	C29H34N6O6
Molecular Weight	562.62 g/mol
Synonyms	Tyr-Pro-Trp-Gly-NH2; L-Tyrosyl-L-prolyl-L-tryptophylglycinamide; Tetrapeptide Amide TFA Salt (common form); YPWGa; H-Tyr-Pro-Trp-Gly-NH2 TFA; 144450-13-5 (CAS); Tyrosine-Proline-Tryptophan-Glycine Amide
EINECS	Contact for details

Quality Control

Our H-Tyr-Pro-Trp-Gly-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Chiral Purity (HPLC)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.