Description

Lamifiban CAS NO 144412-49-7 is a potent and selective non-peptide antagonist of the platelet glycoprotein IIb/IIIa receptor, which plays a critical role in arterial thrombosis. This compound is a key intermediate in the synthesis of pharmaceutical active ingredients designed to inhibit platelet aggregation. It is essential for research and development laboratories, as well as manufacturers, focused on creating next-generation antithrombotic and antiplatelet therapies for cardiovascular diseases.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced antithrombotic drug candidates.
• Biochemical Research: Used in in vitro and in vivo studies to investigate platelet aggregation mechanisms and thrombosis pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Integral to the development and scaling of novel glycoprotein IIb/IIIa inhibitors for cardiovascular applications.

Basic Information

Product Name	Lamifiban
CAS No.	144412-49-7
Molecular Formula	C₂₀H₂₈N₄O₅
Molecular Weight	404.46 g/mol
Synonyms	Ro 44-9883; L-703,014; (2S)-2-[[4-[(4-Amidinophenyl)methoxy]benzoyl]amino]-3-(1H-imidazol-4-yl)propanoic acid; 4-[[4-(Aminoiminomethyl)phenoxy]methyl]-N-[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]benzamide; Lamifibanum [Latin]; UNII-5U8Q9S8K1F
EINECS	Contact for details

Quality Control

Our Lamifiban is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research and development. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced chromatographic techniques. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.