Description

Cholecystokinin-J is a synthetic peptide analog of the gastrointestinal hormone cholecystokinin, designed for high-affinity receptor binding and biological activity. This compound is a critical research tool for studying digestive physiology, satiety signaling, and central nervous system functions. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on metabolic disorders, appetite regulation, and neurogastroenterology.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies investigating cholecystokinin receptor (CCK1 and CCK2) pharmacology and signaling pathways.
• Neuroscience Studies: Applied in research exploring the role of CCK in anxiety, panic disorders, memory, and dopaminergic system modulation within the central nervous system.
• Gastrointestinal Physiology: Employed to study pancreatic enzyme secretion, gallbladder contraction, gastric emptying, and gut-brain axis communication.
• Drug Discovery & Development: Serves as a key intermediate or biological probe in the development of novel therapeutics for obesity, eating disorders, and gastrointestinal diseases.
• Biochemical Assays: Utilized in receptor binding assays, functional cellular assays, and in vitro diagnostic test development to quantify CCK activity or receptor expression.
• Academic & Clinical Research: Supports fundamental and translational research in university and hospital laboratories worldwide.

Basic Information

Product Name	Cholecystokinin-J
CAS No.	144396-38-3
Molecular Formula	C56H73N11O13S2
Molecular Weight	1164.38 g/mol
Synonyms	CCK-J; Cholecystokinin J; CCK-J Peptide; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (sulfated); Sincalide analog; CCK-8 sulfated analog; Cholecystokinin octapeptide (sulfated) analog; [Thr28, Nle31]CCK-(25-33)
EINECS	Contact for details

Quality Control

Every batch of Cholecystokinin-J is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for critical research applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting results for HPLC purity, amino acid analysis, mass spectrometry (MS), and other relevant tests.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak confirmed
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical values
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.