Description

2,3-Difluoro-4-Iodophenol is a halogenated phenol derivative that serves as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents on the phenolic ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoro-iodophenol moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the iodine and phenol functional groups.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated aromatic structures.

Basic Information

Product Name	2,3-Difluoro-4-Iodophenol
CAS No.	144292-40-0
Molecular Formula	C6H3F2IO
Molecular Weight	271.99 g/mol
Synonyms	4-Iodo-2,3-difluorophenol; 2,3-Difluoro-4-iodo-1-hydroxybenzene; 1-Hydroxy-2,3-difluoro-4-iodobenzene; Phenol, 2,3-difluoro-4-iodo-; 2,3-DFIP
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Iodophenol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards expected by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.