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Arginyl-Glycyl-Aspartyl-Tryptophan CAS NO 144161-76-2


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CAS No.:144161-76-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Arginyl-Glycyl-Aspartyl-Tryptophan is a synthetic tetrapeptide composed of the amino acids Arginine, Glycine, Aspartic Acid, and Tryptophan. This sequence is of significant interest in biochemical and pharmaceutical research due to its potential to mimic or interfere with specific protein-protein interaction sites. It is primarily utilized by research institutions and pharmaceutical developers focusing on cell adhesion, signal transduction pathways, and novel therapeutic agent discovery.

Application

  • Biomedical Research: Used as a tool compound to study integrin-mediated cell adhesion and signaling processes.
  • Drug Discovery: Serves as a lead structure or reference standard in the development of anti-thrombotic, anti-cancer, or anti-angiogenic agents.
  • Biochemical Assays: Employed in competitive binding assays and enzyme-linked immunosorbent assays (ELISA) to investigate receptor-ligand interactions.
  • Peptide Synthesis: Acts as a building block or intermediate for the solid-phase or solution-phase synthesis of longer, more complex peptide sequences.
  • Academic Studies: Utilized in university and institutional labs for fundamental research in molecular biology and biochemistry.

Basic Information

Product Name Arginyl-Glycyl-Aspartyl-Tryptophan
CAS No. 144161-76-2
Molecular Formula C27H40N10O8
Molecular Weight 632.67 g/mol
Synonyms Arg-Gly-Asp-Trp; RGDW Peptide; H-Arg-Gly-Asp-Trp-OH; Tetrapeptide Arg-Gly-Asp-Trp; L-Arginylglycyl-L-α-aspartyl-L-tryptophan; RGDW; Arginine-Glycine-Aspartic Acid-Tryptophan; RGDS Analog
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Quality Control

Our Arginyl-Glycyl-Aspartyl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 1.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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