Description

Promastigote Surface Antigen-2 Complex is a high-purity biochemical reagent of significant importance in parasitology and immunology research. This complex is critical for the study of Leishmania parasites, serving as a key antigen for diagnostic assay development and vaccine research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on tropical diseases and immunodiagnostics.

Application

• Immunodiagnostic Development: As a critical coating antigen or capture reagent in ELISA, lateral flow, and other immunoassays for the detection of Leishmania infections.
• Vaccine Research: A target antigen in the development and evaluation of prophylactic and therapeutic vaccines against leishmaniasis.
• Basic Research: Used in parasitology studies to investigate host-parasite interactions, immune evasion mechanisms, and antigenic variation of Leishmania species.
• Serological Testing: Employed as a standard or control in the validation and quality control of commercial diagnostic test kits.
• Antibody Production & Purification: Serves as an immunogen for generating specific polyclonal or monoclonal antibodies in host animals.
• Biomarker Discovery: Aids in the identification and validation of novel biomarkers for disease staging and treatment monitoring.

Basic Information

Product Name	Promastigote Surface Antigen-2 Complex
CAS No.	144132-46-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PSA-2 Complex; Promastigote Surface Antigen 2; Leishmania Surface Antigen Complex; gp46 Complex; PSA-2 Glycoprotein Complex; Metacyclic Promastigote Antigen-2; Infective Stage Surface Antigen-2
EINECS	Contact for details

Quality Control

Our Promastigote Surface Antigen-2 Complex is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing specifications such as protein concentration, purity by SDS-PAGE, endotoxin levels, and functional activity in immunoassays are provided with every shipment to guarantee batch-to-batch consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for single-use applications to maintain optimal activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Immunoblot)	Consistent with PSA-2 complex profile
Protein Content (BCA)	>95%
Purity (SDS-PAGE)	>90%
Endotoxin (LAL)	<1.0 EU/µg
Biological Activity (ELISA)	Reactive with standard reference antisera
Solubility	Soluble in appropriate aqueous buffers
Moisture Content (KF)	<5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.