Description

Vasoactive Intestinal Peptide (1-11) is a specific, biologically active fragment of the full-length Vasoactive Intestinal Peptide (VIP). This synthetic peptide sequence is crucial for research into the structure-activity relationships and receptor binding mechanisms of VIP. It serves as a vital tool for scientists in the fields of neuroendocrinology, immunology, and gastrointestinal physiology. This high-purity peptide is essential for pharmaceutical R&D, academic research, and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating VIP's role in vasodilation, smooth muscle relaxation, and neurotransmission.
• Pharmacology & Drug Discovery: Serves as a key intermediate or lead compound for developing novel therapeutics targeting VIP receptors for conditions like inflammation, pulmonary hypertension, and neurological disorders.
• Immunology Studies: Applied in research exploring the immunomodulatory effects of VIP fragments on cytokine production and T-cell function.
• Diagnostic Development: Utilized in the development and calibration of immunoassays (ELISA, RIA) for detecting VIP and related peptides in biological samples.
• Academic & Institutional Research: A fundamental reagent for university and institutional labs studying peptide hormone signaling pathways and fragment bioactivity.
• Biochemical Reagent: Acts as a substrate or inhibitor in enzymatic studies and receptor binding assays to elucidate specific interaction sites.

Basic Information

Product Name	Vasoactive Intestinal Peptide (1-11)
CAS No.	144119-83-5
Molecular Formula	C60H89N17O16S
Molecular Weight	1352.5 g/mol
Synonyms	VIP (1-11); VIP Fragment 1-11; Vasoactive Intestinal Polypeptide (1-11); H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-OH; VIP 1-11 Peptide; VIP 1-11 amide (common derivative); Vasoactive intestinal peptide 1-11 fragment
EINECS	Contact for details

Quality Control

Our Vasoactive Intestinal Peptide (1-11) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets exacting research-grade specifications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, peptide content, and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.