Description

Ala-Pro-Gly-Trp-NH2 Acetate Salt is a high-purity, synthetic tetrapeptide derivative, supplied as an acetate salt for enhanced stability and solubility. This compound is a critical building block in advanced pharmaceutical research and development, particularly for studying peptide structure-activity relationships and metabolic pathways. It is essential for researchers and manufacturers in the fields of drug discovery, biochemical research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel peptide-based therapeutics.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to investigate protease activity and specificity.
• Drug Discovery: Acts as a core structural motif for developing new candidates targeting various diseases, including metabolic disorders.
• Academic Research: Employed in university and institutional labs for fundamental studies on peptide chemistry, folding, and bioactivity.
• Peptide Library Synthesis: A valuable component in the construction of combinatorial peptide libraries for high-throughput screening.
• Standards & Calibration: Utilized as a certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	Ala-Pro-Gly-Trp-NH2 Acetate Salt
CAS No.	144110-40-7
Molecular Formula	C27H36N8O6 • xC2H4O2
Molecular Weight	568.63 g/mol (Free base)
Synonyms	APGW-NH2 Acetate Salt; H-Ala-Pro-Gly-Trp-NH2 Acetate; Alanine-Proline-Glycine-Tryptophan Amide Acetate; Tetrapeptide APGW-NH2 Acetate; L-Alanyl-L-prolylglycyl-L-tryptophanamide acetate; 144110-40-7 (Acetate); APGWamide Acetate Salt
EINECS	Contact for details

Quality Control

Every batch of Ala-Pro-Gly-Trp-NH2 Acetate Salt is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/Titration)	Conforms
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.