Description

Galanin (1-13)-Spantide I is a synthetic peptide analog designed as a potent antagonist of the neuropeptide galanin, specifically targeting its receptor subtype 1 (GalR1). This compound is a critical research tool for elucidating the complex roles of galanin in physiological and pathological processes within the central and peripheral nervous systems. It is essential for neuroscientists, pharmacologists, and drug discovery teams investigating pain modulation, feeding behavior, memory, and neuroendocrine function.

Application

• Neuroscience Research: Used as a selective GalR1 antagonist to study galanin's involvement in nociception, mood disorders, and cognitive functions.
• Pharmacological Studies: Serves as a reference standard in receptor binding assays and functional studies to characterize galanin receptor signaling pathways.
• Drug Discovery: A key compound for screening and developing novel therapeutic agents targeting galanin-related conditions like chronic pain, epilepsy, and addiction.
• Academic & Institutional Research: Fundamental tool for in vitro and in vivo experiments to map galaninergic systems and their physiological impacts.
• Biochemical Analysis: Employed in the development and validation of analytical methods, such as HPLC and mass spectrometry, for peptide quantification.

Basic Information

Product Name	Galanin (1-13)-Spantide I
CAS No.	143868-20-6
Molecular Formula	C78H115N23O18S
Molecular Weight	1634.9 g/mol
Synonyms	Galanin (1-13)-Spantide; [D-Trp2, D-Ala5, D-Pro8-13]-Galanin(1-13); Galanin Receptor Antagonist; Spantide I (galanin antagonist); Galanin(1-13) antagonist; Galanin message-associated peptide antagonist; GAL(1-13)-Spantide I
EINECS	Contact for details

Quality Control

Every batch of Galanin (1-13)-Spantide I is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of identity, purity, and potency. Our quality commitment includes comprehensive characterization by HPLC, mass spectrometry, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with each shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.