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H-Gly-Gly-Trp-Ser-His-Trp-Oh CAS NO 143740-28-7


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CAS No.:143740-28-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

H-Gly-Gly-Trp-Ser-His-Trp-Oh is a synthetic hexapeptide sequence containing the amino acids glycine, tryptophan, serine, and histidine. This compound is of significant interest in biochemical research and pharmaceutical development due to its specific sequence, which may mimic bioactive regions of larger proteins. It is primarily utilized by research institutions and biotechnology companies focused on peptide synthesis, structure-activity relationship (SAR) studies, and the development of novel therapeutic agents.

Application

  • Biochemical Research: Used as a standard or reference compound in peptide characterization studies.
  • Pharmaceutical R&D: Serves as a key intermediate or a model peptide in the development of new drug candidates, particularly in oncology and neurology.
  • Enzyme Substrate Studies: Potential substrate for investigating protease or kinase activity due to its specific amino acid sequence.
  • Antigen Synthesis: Can be used in the synthesis of peptide antigens for antibody production and immunological assays.
  • Structure-Activity Relationship (SAR): Fundamental for studying how peptide sequence alterations affect biological function and binding affinity.
  • Academic Research: Employed in university laboratories for teaching and advanced research in peptide chemistry and molecular biology.

Basic Information

Product Name H-Gly-Gly-Trp-Ser-His-Trp-Oh
CAS No. 143740-28-7
Molecular Formula C38H45N11O9
Molecular Weight 799.84 g/mol
Synonyms Gly-Gly-Trp-Ser-His-Trp; GGW-S-H-W-OH; Hexapeptide GGW-S-H-W; H-Gly-Gly-Trp-Ser-His-Trp; H-Gly-Gly-Trp-Ser-His-Trp-OH; GGW-S-H-W Peptide; (Gly)2-Trp-Ser-His-Trp; L-Glycyl-L-glycyl-L-tryptophyl-L-seryl-L-histidyl-L-tryptophan
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Quality Control

Our H-Gly-Gly-Trp-Ser-His-Trp-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry for identity confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For short-term use, store desiccated at 2-8°C.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 1.0%
Amino Acid Composition Conforms
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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