Description

Rocuronium is a non-depolarizing neuromuscular blocking agent belonging to the aminosteroid class, widely recognized for its rapid onset of action. Its primary value lies in providing safe and effective skeletal muscle relaxation during surgical procedures and endotracheal intubation. This high-purity pharmaceutical intermediate is essential for manufacturers in the pharmaceutical and fine chemical sectors developing injectable anesthetic formulations.

Application

• Pharmaceutical Active Ingredient (API): Core component in the synthesis of injectable neuromuscular blocking agents for general anesthesia.
• Surgical Muscle Relaxation: Used in formulations to facilitate endotracheal intubation and provide muscle paralysis during surgery.
• Critical Care Medicine: Employed in ICU settings to enable mechanical ventilation in critically ill patients.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological and clinical research studies.
• Generic Drug Manufacturing: Critical raw material for producers of generic rocuronium bromide injection products.
• Chemical Synthesis: Advanced intermediate for further chemical modification in specialty fine chemical production.

Basic Information

Product Name	Rocuronium
CAS No.	143558-00-3
Molecular Formula	C32H53N2O4+
Molecular Weight	529.78 g/mol (as cation)
Synonyms	Rocuronium cation; 1-[17β-(Acetyloxy)-3β-hydroxy-2β-(1-piperidinyl)-5α-androstan-16β-yl]-1-(2-propenyl)pyrrolidinium; Org 9426; (2β,3α,5α,16β,17β)-17-(Acetyloxy)-2-(1-piperidinyl)-androstan-16-yl-1-methyl-1-propenylpyrrolidinium; ZEMURON (as bromide salt); Esmeron (as bromide salt)
EINECS	Contact for details

Quality Control

Our Rocuronium is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical use. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, and stringent controls for related substances and residual solvents. A Certificate of Analysis (COA) documenting full compliance with agreed specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.