Description

Biotinyl-(Leu8,D-Trp22,Tyr25)-Somatostatin-28 is a biotinylated, modified somatostatin-28 analog designed for advanced research applications. This peptide is engineered for high-affinity binding and is a critical tool in receptor studies and targeted biochemical assays. It is primarily utilized by pharmaceutical researchers, academic institutions, and diagnostic developers working in endocrinology, oncology, and neurobiology.

Application

• Biochemical Research: A key ligand for studying somatostatin receptor (SSTR) subtypes, their distribution, and signaling pathways.
• Drug Discovery: Used in high-throughput screening (HTS) assays to identify and characterize novel SSTR-targeting therapeutic candidates.
• Diagnostic Probe Development: Serves as a targeting moiety for developing imaging agents and diagnostic tools due to its biotin tag for facile conjugation.
• Affinity Purification: Employed in pull-down assays and affinity chromatography to isolate and study receptor complexes.
• Cell Biology Studies: Utilized to investigate the internalization and trafficking of somatostatin receptors in various cell lines.
• Preclinical Modeling: Applied in animal models of diseases where somatostatin pathways are implicated, such as certain cancers and endocrine disorders.

Basic Information

Item	Detail
Product Name	Biotinyl-(Leu8,D-Trp22,Tyr25)-Somatostatin-28
CAS No.	143519-58-8
Molecular Formula	C149H220N38O39S2
Molecular Weight	~3299.8 g/mol
Synonyms	Biotin-Somatostatin-28 (Leu8,D-Trp22,Tyr25); Biotinyl-Somatostatin-28 Analog; Biotin-SST-28; Somatostatin-28 Biotin Conjugate; Biotinylated Somatostatin-28 Derivative; [Leu8,D-Trp22,Tyr25]-Somatostatin-28-Biotin; Research Peptide 143519-58-8
EINECS	Contact for details

Quality Control

Our Biotinyl-(Leu8,D-Trp22,Tyr25)-Somatostatin-28 is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content. We adhere to GMP principles for research-grade peptides, and specifications can be aligned with specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.