Description

4(1H)-Pyrimidinone, 6-Amino-2-Hydroxy- (9Ci) is a high-purity heterocyclic organic compound with the CAS number 143519-02-2, serving as a critical building block in advanced chemical synthesis. Its unique pyrimidinone core structure makes it an invaluable intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate and scale complex molecular architectures.

Application

This versatile chemical intermediate enables synthesis across several high-value sectors. Key application areas include:

• Pharmaceutical Intermediate: Serves as a core scaffold for the research and development of novel antiviral, anticancer, and antimicrobial agents.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and plant growth regulators with targeted activity.
• Fine Chemical Production: Acts as a key precursor for synthesizing complex dyes, pigments, and functional materials.
• Biochemical Research: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Nucleoside Analog Development: Useful in the synthesis of modified nucleosides and nucleotides for therapeutic applications.

Basic Information

Product Name	4(1H)-Pyrimidinone, 6-Amino-2-Hydroxy- (9Ci)
CAS No.	143519-02-2
Molecular Formula	C4H5N3O2
Molecular Weight	127.10 g/mol
Synonyms	6-Amino-2-hydroxypyrimidin-4(1H)-one; 6-Amino-2-hydroxypyrimidin-4(3H)-one; 6-Amino-2-hydroxypyrimidin-4-ol; 2-Hydroxy-6-aminopyrimidin-4(3H)-one; 6-Amino-4-hydroxy-2(1H)-pyrimidinone; 6-Amino-2-pyrimidinol-4-one; 4-Hydroxy-6-aminopyrimidin-2(1H)-one; AHPO
EINECS	Contact for details

Quality Control

Our 4(1H)-Pyrimidinone, 6-Amino-2-Hydroxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including HPLC purity, NMR, and IR confirmation, to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.