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5-Fluoro-2-[2-(5-Fluoro-4-Oxo-3H-Pyrimidin-2-Yl)Phenyl]-3H-Pyrimidin-4 -One CAS NO 143501-89-7
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CAS No.:143501-89-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Fluoro-2-[2-(5-Fluoro-4-Oxo-3H-Pyrimidin-2-Yl)Phenyl]-3H-Pyrimidin-4 -One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of targeted therapeutics.
Application
- Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules, particularly in oncology and antiviral research.
- Active Pharmaceutical Ingredient (API) Development: Used as a core scaffold for constructing novel APIs with potential therapeutic activity.
- Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibition, receptor binding, and other biological mechanisms.
- Process Chemistry & Scale-Up: Supplied for optimization and kilogram-scale production runs in process development laboratories.
- Reference Standard: High-purity grades are suitable for use as analytical reference standards in quality control and method development.
Basic Information
| Item | Details |
|---|---|
| Product Name | 5-Fluoro-2-[2-(5-Fluoro-4-Oxo-3H-Pyrimidin-2-Yl)Phenyl]-3H-Pyrimidin-4 -One |
| CAS No. | 143501-89-7 |
| Molecular Formula | C14H6F2N4O2 |
| Molecular Weight | 300.22 g/mol |
| Synonyms | 5-Fluoro-2-[2-(5-fluoro-4-oxo-3,4-dihydropyrimidin-2-yl)phenyl]pyrimidin-4(3H)-one; 2-(2-(5-Fluoro-4-oxo-3H-pyrimidin-2-yl)phenyl)-5-fluoro-3H-pyrimidin-4-one; 143501-89-7; FC-101 (Research Code); Bicyclic Fluoro-Pyrimidinone Derivative |
| EINECS | Contact for details |
Quality Control
Every batch of 5-Fluoro-2-[2-(5-Fluoro-4-Oxo-3H-Pyrimidin-2-Yl)Phenyl]-3H-Pyrimidin-4 -One is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, NMR, and MS. Our quality commitment ensures material suitability for demanding applications in pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC/MS) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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