Description

H-Gly-Ala-Gly-Oh·Hcl is a high-purity, protected tripeptide derivative, specifically the hydrochloride salt of the C-terminal carboxylic acid of the Gly-Ala-Gly sequence. This compound serves as a critical building block in solid-phase peptide synthesis (SPPS) and is essential for researchers and manufacturers requiring precise control over peptide chain assembly. It is primarily utilized by the pharmaceutical, biotechnology, and life science research sectors for developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a protected amino acid derivative for the controlled elongation of peptide chains in automated synthesizers.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies and proteomics research.
• Cosmetic Peptide Development: Incorporated into the design of bioactive peptides for skincare and cosmetic formulations.
• Antigen Synthesis: Employed in the production of specific peptide sequences for antibody generation and immunological studies.

Basic Information

Product Name	H-Gly-Ala-Gly-Oh·Hcl
CAS No.	143485-62-5
Molecular Formula	C8H15N3O4·HCl
Molecular Weight	253.68 g/mol
Synonyms	Glycyl-L-alanylglycine hydrochloride; H-Gly-Ala-Gly-OH hydrochloride; GAG-OH·HCl; Tripeptide Gly-Ala-Gly hydrochloride; N-(N-Glycyl-L-alanyl)glycine hydrochloride; L-Alanine, glycylglycyl-, hydrochloride (1:1); Boc-Gly-Ala-Gly-OH deprotected hydrochloride salt (common precursor form); Protected Gly-Ala-Gly C-terminal acid HCl salt
EINECS	Contact for details

Quality Control

Our H-Gly-Ala-Gly-Oh·Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccated environments at lower temperatures (2-8°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.