Description

2-(Trifluoromethyl)Quinolin-6-Ol is a high-value fluorinated quinoline derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both a quinoline core and a trifluoromethyl group, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly in developing molecules for oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in creating novel pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science: Acts as a building block for advanced organic electronic materials, such as ligands for OLEDs or components for organic semiconductors.
• Chemical Synthesis: Employed in medicinal and combinatorial chemistry for library synthesis and structure-activity relationship (SAR) studies.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the introduction and study of fluorine atoms in complex heterocycles.

Basic Information

Product Name	2-(Trifluoromethyl)Quinolin-6-Ol
CAS No.	143465-21-8
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	6-Hydroxy-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-6-quinolinol; 2-Trifluoromethylquinolin-6-ol; 6-Quinolinol, 2-(trifluoromethyl)-; Quinolin-6-ol, 2-(trifluoromethyl)-; 143465-21-8; 2-TFMQ-6-Ol
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Quinolin-6-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.