Description

Permafloxacin CAS NO 143383-65-7 is a synthetic fluoroquinolone antibiotic compound. It is valued for its potent antibacterial activity against a broad spectrum of Gram-positive and Gram-negative pathogens. This active pharmaceutical ingredient (API) is primarily required by the pharmaceutical industry for research and development of novel antibacterial therapies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced fluoroquinolone antibiotic formulations.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate mechanisms of action and resistance.
• Veterinary Medicine Development: Applied in R&D for creating treatments for bacterial infections in animals.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Permafloxacin
CAS No.	143383-65-7
Molecular Formula	C19H20FN3O4
Molecular Weight	373.38 g/mol
Synonyms	Permafloxacin; 1-Cyclopropyl-6-fluoro-7-(4-methylpiperazin-1-yl)-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; PD 140288; PD-140288; (+-)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(4-methyl-1-piperazinyl)-4-oxo-; (±)-Permafloxacin
EINECS	Contact for details

Quality Control

Our Permafloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.