Description

Toborinone CAS NO 143343-83-3 is a selective phosphodiesterase III (PDE III) inhibitor, a high-purity chemical compound of significant interest in pharmaceutical research and development. Its primary value lies in its potent inotropic and vasodilatory properties, making it a key candidate for the study of cardiovascular therapeutics. This compound is essential for researchers and manufacturers in the pharmaceutical industry focused on developing treatments for heart failure and related cardiac conditions.

Application

• Primary use as a reference standard in analytical chemistry for quality control and method validation.
• Critical pharmaceutical intermediate in the synthesis of novel cardiovascular drugs.
• Active pharmaceutical ingredient (API) for preclinical and clinical research into heart failure management.
• Biochemical tool for studying PDE III enzyme inhibition and related cellular signaling pathways.
• Component in formulation development for injectable or oral dosage forms.
• Used in pharmacology studies to investigate inotropic and vasodilatory effects.

Basic Information

Product Name	Toborinone
CAS No.	143343-83-3
Molecular Formula	C20H24N2O5
Molecular Weight	372.42 g/mol
Synonyms	1,2,3,4-Tetrahydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-isoquinolinone; OPC-8490; Toborinon; Toborinonum; (6-(4-(3,4-Dimethoxybenzoyl)piperazin-1-yl)-3,4-dihydro-1H-isoquinolin-2-one)
EINECS	Contact for details

Quality Control

Our Toborinone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified purity criteria.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.