Description

5-Fluoro-2-Phenylpyrimidin-4-Ol is a high-purity, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Fluoro-2-Phenylpyrimidin-4-Ol
CAS No.	143328-90-9
Molecular Formula	C10H7FN2O
Molecular Weight	190.18 g/mol
Synonyms	5-Fluoro-2-phenyl-4-pyrimidinol; 4-Pyrimidinol, 5-fluoro-2-phenyl-; 5-Fluoro-2-phenylpyrimidin-4(3H)-one; 5-Fluoro-2-phenyl-4(1H)-pyrimidinone; 5-Fluoro-2-phenyl-4-hydroxypyrimidine; 143328-90-9; 5-Fluoro-2-phenyl-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Phenylpyrimidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.