Description

6-(Trifluoromethyl)-7-Oxo-8-Ribityllumazine is a specialized fluorinated lumazine derivative, a key intermediate in the synthesis of complex bioactive molecules. Its value lies in the unique trifluoromethyl group, which can significantly enhance metabolic stability and lipophilicity in target compounds. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, particularly for scientists working on novel enzyme inhibitors, fluorescent probes, and advanced chemical libraries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those targeting enzymatic pathways where the lumazine scaffold is active.
• Agrochemical Research: Used in developing advanced active ingredients, where the trifluoromethyl group contributes to improved pesticidal or herbicidal activity and environmental persistence.
• Biochemical Probe Development: Serves as a precursor for creating fluorescent or tagged molecular probes to study riboflavin biosynthesis and related metabolic processes.
• Chemical Biology: Employed in fragment-based drug discovery and the construction of specialized chemical libraries for high-throughput screening.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting fundamental studies in organic chemistry, medicinal chemistry, and enzymology.

Basic Information

Product Name	6-(Trifluoromethyl)-7-Oxo-8-Ribityllumazine
CAS No.	143309-76-6
Molecular Formula	C12H15F3N4O7
Molecular Weight	360.26 g/mol
Synonyms	8-Ribityl-6-(trifluoromethyl)lumazine; 6-(Trifluoromethyl)-7,8-didemethyl-8-ribityllumazine; 6-Trifluoromethyl-7-oxo-8-ribityl-7,8-dihydropteridine-2,4(1H,3H)-dione; 6-(Trifluoromethyl)-7-oxo-8-D-ribityl-7,8-dihydrolumazine; Trifluoromethylribityllumazine
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-7-Oxo-8-Ribityllumazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.