Description

(S)-(+)-2-Amino-2-Methylbutanedioic Acid Hydrochloride Salt CAS NO 143282-41-1 is a high-purity, single-enantiomer chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a precursor for the synthesis of complex molecules, particularly in the development of pharmaceuticals and bioactive compounds. This product is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require optically pure intermediates for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in neurologic and metabolic disorder treatments.
• Asymmetric Catalyst Ligand Synthesis: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Peptidomimetics Research: Serves as a constrained amino acid analog in the design and synthesis of novel peptide-based drugs.
• Agrochemical Active Ingredient Development: Intermediate in the production of enantiomerically pure herbicides and pesticides.
• Fine Chemical Synthesis: Versatile intermediate for creating specialty chemicals with high stereochemical purity.
• Biochemical Research: Used in studies of enzyme mechanisms and as a substrate analog in biochemical assays.

Basic Information

Product Name	(S)-(+)-2-Amino-2-Methylbutanedioic Acid Hydrochloride Salt
CAS No.	143282-41-1
Molecular Formula	C5H10ClNO4
Molecular Weight	183.59 g/mol
Synonyms	(S)-2-Amino-2-methylsuccinic acid hydrochloride; (S)-(+)-2-Amino-2-methylbutanedioic acid hydrochloride; L-2-Amino-2-methylsuccinic acid hydrochloride; (2S)-2-Amino-2-methylbutanedioic acid hydrochloride; (S)-2-Methylaspartic acid hydrochloride; (S)-α-Methylaspartic acid hydrochloride; (S)-2-Amino-2-methyl-1,4-butanedioic acid hydrochloride; (S)-2-Amino-2-methylsuccinate hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Amino-2-Methylbutanedioic Acid Hydrochloride Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) for assay, enantiomeric excess (ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.