Description

Cyclo(-D-Tyr-Arg-Gly-Asp-Cys (Carboxymethyl)-Oh) Sulfoxide is a synthetic, cyclic peptide derivative containing the Arg-Gly-Asp (RGD) motif and a carboxymethylated cysteine sulfoxide modification. This compound is of significant interest in advanced biomedical research and development due to its potential role in modulating cell adhesion and signaling pathways. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on oncology, cardiovascular disease, and novel therapeutic targeting.

Application

• Biomedical Research: Investigation of integrin-mediated cell adhesion, migration, and signaling mechanisms.
• Drug Discovery: Serving as a key intermediate or lead compound in the development of targeted cancer therapies and anti-angiogenic agents.
• Diagnostic Development: Potential use in the design of imaging probes for detecting specific cell surface receptors.
• Peptide Chemistry Studies: A model compound for studying the synthesis, stability, and activity of modified cyclic RGD peptides.
• Biomaterial Functionalization: Coating or conjugating to surfaces to create bioactive materials that influence cell behavior.

Basic Information

Product Name	Cyclo(-D-Tyr-Arg-Gly-Asp-Cys (Carboxymethyl)-Oh) Sulfoxide
CAS No.	143120-27-8
Molecular Formula	C28H41N9O11S2
Molecular Weight	743.81 g/mol
Synonyms	c(D-Tyr-Arg-Gly-Asp-Cys(S-CH2COOH)) Sulfoxide; Cyclic RGD Peptide Sulfoxide Derivative; c(DYRGD-CM-Cys) Sulfoxide; Cyclo(D-Tyr-Arg-Gly-Asp-Cys(S-carboxymethyl)) Sulfoxide; c(RGDyC(S-CH2COOH)) Sulfoxide; 143120-27-8; Cyclic Pentapeptide Sulfoxide
EINECS	Contact for details

Quality Control

Our Cyclo(-D-Tyr-Arg-Gly-Asp-Cys (Carboxymethyl)-Oh) Sulfoxide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.